Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0414875
PubChem CID
Molecular Formula
C24H19N2NaO5S
Molecular Weight
470.482 g/mol
Synonyms/Alias
[GoSlo SR 5-69; 1363419-31-1; GoSlo-SR-5-69; sodium 1-amino-9;10-dioxo-4-((5;6;7;8-tetrahydronaphthalen-2-yl)amino)-9;10-dihydroanthracene-2-sulfonate; sodium;1-amino-9;10-dioxo-4-(5;6;7;8-tetrahydron...
InChI Key
JOJJZTFRBZWSBX-UHFFFAOYSA-M
InChI
InChI=1S/C24H20N2O5S.Na/c25-22-19(32(29,30)31)12-18(26-15-10-9-13-5-1-2-6-14(13)11-15)20-21(22)24(28...
IUPAC Name
sodium;1-amino-9,10-dioxo-4-(5,6,7,8-tetrahydronaphthalen-2-ylamino)anthracene-2-sulfonate
CAS Number
1363419-31-1

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

52 55 0 0 0 0 0 0 0 0999 V2000
-6.1371 -0.0096 0.9906 C 0 0 0 0 0 0 0 0 0 0 0 0
-5.4077 1.3102 0.7418 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.8961 1.122...

Experimental Data

Activity Data

Target Ion Channel
large conductance calcium activated potassium channels (KCa1.1)
Uniprot Accession Number
Function
Activator
Species
Oryctolagus cuniculus (Rabbit)
IC50
N/A (Not available)
EC50
EC50: 251 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−150 to 50 mV mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
33
Rotatable Bonds
3
logP
0.5747
Complexity
118.4913
TPSA (Ų)
129.39
H-Bond Donors
2
H-Bond Acceptors
7
Ring Count
5
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